C'est la vie or caught between a rock and a hard place

A risky but bold work of art by Fiona, age 4. One cannot escape risk.

Wednesday my wife and I met with a doctor, an expert in stroke treatment. He is associated with both University Hospital and with the Robarts Research Institute. He laid out the detailed findings from the investigation into the health of my arteries down on the desk. He looked at us for a moment and then told me, "You are trapped between a rock and a hard place."

The tests revealed the arteries in my neck are laden with plaque. My arteries hold three times the amount of plaque as that found in healthy men of my age. This plaque can flake and the small bits can be carried in the blood to the brain. This explains the TIAs, transient ischemic attacks, I have been having. TIAs, also known as "mini-strokes", are taken very seriously by doctors as they can be harbingers of a massive stroke in one's future.

I already take some pretty powerful medications. If all had gone well with these recent tests, I might have had some of my meds cutback. Strong meds often carry risks. Instead, I was given another cholesterol fighting drug which will also boost the benefits gained from the statin I am already taking. These drugs can mess with some important chemicals in the body. To counter this I must add 200mg of another drug taken twice a day. Unfortunately, this drug can increase the bleeding potential resulting from taking the anticoagulant Pradaxa. I take Pradaxa.

My history of heart arrhythmia demands I take an anticoagulant. Arrhythmias increase the risk of blood clots forming in the heart. These can then travel to the brain. An anticoagulant cuts this risk. Unfortunately, because micro bleeding was discovered in my brain, I cannot take the common and inexpensive anticoagulant Coumadin. It would increase my risk of having an uncontrolled cranial bleed.

There is an alternative, the anticoagulant Pradaxa. It will lessen my chance of stroke without increasing my risk of bleeding in the brain. The downside is that Pradaxa is expensive, very expensive, and if I should have a serious bleeding problem, for any reason, the blood thinning achieved by Pradaxa cannot be as quickly reversed as it can with Coumadin.

Yes, I am trapped between a rock and a hard place. But, I am not alone. I am trapped there with my doctors. They have no perfect answers to my health problems. Try this and that may go wrong. Try that and this may go wrong. And either answer is accompanied by the risk of some truly awful side effects, of unwanted consequences.

Our blood clots for good reason. There is no mystery as to why anticoagulants carry risks. All my drugs mess with important functions in my body and messing with those functions is risky. Period. Being a doctor is all about balancing risk. Doctors do a damn amazing job at balancing those risks. I am in awe of the talents, the skills, the knowledge and the bold risk-taking of my doctors.

It was more than a decade ago that I had the mitral valve in my heart repaired robotically. I was the first person in Canada to have such an operation. It was risky but it was clearly worth the risk. My ICD/pacemaker was a risk, some doctors questioned whether I actually needed one. Today my heart is being paced 93 percent of the time. I have had my heart rebooted by my built-in defibrillator at least three times. My doctors and I have taken a lot of risks over the years and so far they have made the right calls.

As of today, I am taking a mixture of ten tables and capsules a day. I chew 'em; I wash 'em down with water; I take 'em with food; I take 'em on an empty stomach. I never did a lot of drugs as a young man growing up in the '60s, but as a senior my world is veering toward Jefferson Airplane country and the land of the white rabbit.

One pill makes you larger,
And one pill makes you small,
And the ones that mother gives you,
Don’t do anything at all (maybe but doubtful).

If I should have a stroke, I know my doctors will wonder what could they have done differently. If I am lucid after the event, I will tell them there is nothing they could have done differently. Nothing. They balanced the risks and we lost.

C'est la vie.

It's a wonderful life!

I'm pushing 67. I'm retired. My heart is failing — slowly. This is not the life I expected to be living in my senior years.

I planned on traveling in my retirement. I still long to visit Romania and Bulgaria. Yes, Romania and Bulgaria. Why? It's a long story and not too relevant today as my chances of actually visiting those countries is fading with each passing day. Getting insurance may be impossible and no insurance means no trip.

Still, I'm happy — exceedingly happy. I have found a sweet spot in life of which I had not an inkling when I was young. One's senior years are, to steal the words of Rod Serling, "A dimension not only of sight and sound, but of mind." With a positive outlook, a willingness to take delight in the moment, life is grand.

I have three grandchildren. It doesn't get any better than that — unless you have four.

I've read that we tend to dwell more on unpleasant events in our lives and to use stronger words to describe them than happy ones. Not me. Don't get me wrong. I love a good personal disaster story as much as anyone. Ask me about sailing. I can tell as good a terror-filled sailing tale as the next sailor but press me and I'll slip into wonderful memories from my days of solo sailing. I loved to sit at the front of my boat, legs straddling the sharply pointed bow and dangling so low that my feet got wet from the surge forward as the boat slashed through the waves of Lake Huron. I'd sit leaning forward with arms resting on the stainless steel bow pulpit.

I loved solo sailing. I'd put my one-degree robot at the helm, a black English autopilot, I'd grab a beer and relax. Drinking on a large sailboat was not illegal back then. Trust me, there is nothing like a cold one enjoyed all alone on a sailboat thrust by the wind into a darkening night. (And yes, I did wear a harness. Fall off a boat with Auto at the helm and the boat will simply sail away.)

I also recall my English roadster — a Morgan — another wonderful memory maker. My Morgan didn't just take me places, it took me to new places. Unheard of places. Places in need of discovery. And it didn't just take me there but it also reveled in revealing the people living in those hidden places. My Morgan spent its first years of our life together traveling the American South: Kentucky, Tennessee, Georgia, Alabama, Mississippi were among its favourite destinations.

I vividly recall one of my best Morgan adventures: Corinth, Mississippi. Need I say more? Back then the bars in the Deep South were among the greatest dive bars in the world. Cheap beer, even cheaper burgers, great music — the musicians were often back up players from Nashville earning a little extra cash — and did I say buckets of cheap beer?

I wore my hair long back then and when I entered the bar in Corinth I had just about the longest hair in the place. If it had been possible for the place to go quiet, my entrance would have done it. But it wasn't possible and it didn't. The rock and roll alternated with country and western and both pounded not just one's ear drums but one's whole body. Good time rock and roll pounded down the local's resistance to the long haired foreigner trespassing on their turf. I spent the night drinking and dancing and measuring my hair length against all comers. I bested a lot of women whose tightly bouffanted locks were teased high and tight on top of their heads. There wasn't a man who could compete with me, nor would have wanted to. When the bar closed the party didn't stop; It moved.

Away from the prying eyes at the bar, the women let their hair down, so to speak, and the who-has-the-longest hair contest began anew.

According to the New York Times, Roy F. Baumeister, a professor of social psychology at Florida State University, wrote a paper Bad Is Stronger Than Good after conducting research showing this is a basic and wide-ranging principle. Bad emotional experiences supposedly have more impact than good ones. They are quicker to form and harder to forget than good experiences. It is simply human nature, he claimed.

Not for me. I have to admit that I spent a lifetime rehashing bad times but no more. Time is short and getting shorter. I have discovered that not only do I no longer dwell on the bad stuff, I can hardly remember the worst stuff. It is all fading as well it should. Remembering the past so that history does not repeat itself has its place when one is younger, I guess, but now, in my senior years, there is little danger of repeating those painful missteps.

People make up the biggest chunk of my good memories. My friends from my childhood, my chums from my youth, my school buds. I have good memories of employers and neighbours and even passing acquaintances. As Maude positively tells Harold when talking about people: "They're my species."

I've know a lot of wonderful people. Some are famous and can easily be found by searching the Net — like the super-achieving Denny Wilcher who gained fame as a conscientious objector during the Second World War. I met Wilcher when he and his wife Ida were  living in Berkeley, California, along with their two youngest daughters. Another somewhat well known person from my past was photographer Andy Whipple who recently passed away. He had just completed a fine art book documenting the Columbia River. Another remarkable person I am proud to know is the Canadian author Joan Barfoot, author of numerous best-selling novels. (I first met Joan Barfoot when she was still an editor for The London Free Press.)

And then there are the wonderful people I have had the luck of knowing but who seem to have passed under the Internet radar. Think of John Hoffman, one of the founders of Big V pharmacies in Ontario. Today both Mr. Hoffman and Big V are gone. There is little to be found about Mr. Hoffman despite the role he played in creating one of the biggest, most successful drugstore chains in Ontario history.

For years, I ran a seminar for photojournalists. In my role as chair of the seminar I met people like Pulitzer Prize-winning photojournalist, Eddie Adams, who, in his role as a combat photographer in Vietnam, produced many powerful images of the war. The first evening of the annual seminar I sponsored a speakers' dinner. Sitting next to, and across from, some of the greatest news shooters in the world was an honour and a delight.

I believe my senior years are a time for both enjoying the present and savouring the past. At this late stage in my life, dwelling on the bad is of no value. It is time, as my granddaughter says, to "just let it go." In keeping with this suggestion, I'm going to go open a beer and think good if somewhat alcohol-blurred thoughts.

Cheers!

It's art!

About a month ago Mike Moffatt, an assistant professor at Ivey business school at Western University, in London, Ontario, discovered an apparently coded note tucked into a book in the university library. Curious as to the meaning, Moffatt offered a hundred dollars to anyone who could solve the riddle.

Today the riddle has been solved. The note found by Moffatt is art. Jordan Himelfarb, a member of the Toronto Star editorial board, followed the clues. They led him to the Western University fine art department and Kelly Jazvac.

Himelfarb traveled from Toronto to London to meet Jazvac at a London coffee shop:

She explained that the Weldon code was an art project that came out of a second-year sculpture and installation class she taught in 2012. The artist, then an undergraduate student, placed 121 letters in the Weldon stacks and moved on with her or his (but probably her) life. Jazvac told me the artist was shocked by the project’s recent fame and wished to remain anonymous lest she be treated unkindly in the media.

The reporter discovered the symbols correspond to capital and lower case letters but the order is random, making the code impossible to crack. For the full story read Himelfarb's interesting story in The Star: I cracked the code at the Western University library.

I'm not surprised at the outcome. Using the Internet and social media I contacted visual artists, writers and poets around the globe. Most of those contacted replied to my inquiry. The majority felt the apparently coded works were art. Some suggested that I google "asemic writing." The local paper, The London Free Press, was onto this art lead but failed to pursue this thread to its logical end.

A Free Press story reported Peter Schwenger of Western had contacted the paper. "I’m pretty sure that these are examples of asemic writing ­— that is, art that looks like writing but is not intended to communicate a meaning, only to represent the feel of writing," he told the paper in an e-mail.

A number of the artists I contacted said the works found in the Western library reminded them of the lettrist movement from the '50s. To my surprise, one artist attacked the concept of asemic writing. The works were lettrist as there is no such thing as asemic writing. "It's a philosophic misnomer," I was told.

As a retired newspaper photographer, an old geezer whose free time is being consumed by trips to the hospital as doctors investigate a genetic-based heart condition, I decided that a trip to the fine art department at Western was the next logical step but I simply didn't have the time. The Toronto Star writer did and I doff my hat to his stick-to-intuitiveness.

The big riddle left unanswered is why did it take a Toronto reporter to track down the answer at Western? The Toronto Star broke the story Saturday. The London Free Press reported the riddle was solved Sunday.

There are a number of online newspapers that essentially ripoff the mainstream media for stories, rewrite them and publish them online as their own. I find this practice disgusting but it is not unique to these online journalistic vultures. The MSM has done this for years, ripping off competing media outlets. It appears that Sunday the online version of The Free Press ripped off the Saturday Star and without so much as a credit in passing.

And here is one last riddle: Why are newspapers failing in this electronic age? Hint: There are clues in the media handling of the strange notes found in the Western library.

OER & Language Learning: Internet Specific Tools

I've mentioned this before but today I got an e-mail that brought the idea of open educational resources back into my mind. If such an online approach was well done, I can envision certain students completing a course online without ever attending a class. Later they could take an exam to prove their competency, earn a credit towards a degree and move on.

I knew a girl who entered high school fluent in at least four languages. Forcing her to take years of high school French was insane. She should have been offered the chance to write all the appropriate exams and put the entire French curriculum behind her. Heck, she spoke French better than some of her teachers. They asked her questions because she not only knew Parisienne French, she new Quebecois. She had lived in France and now that she lived in Canada she was spending her summers in Montreal.

A few years ago, I took a French language course from Western University in London. It was not a good experience. There were too many students and not enough instruction. It was an unfocused course that ran for a number of weeks and then just ended. There was no homework during the course and no exam at the end. The university took my money but gave me little in return. It was a no credit class and with good reason.

That course left me thinking: There must a better way to teach French to English-speaking Canadians. My curiosity led me to The Center for Open Educational Resources & Language Learning (COERLL) at The University of Texas. COERLL is one of 15 National Foreign Language Resource Centers funded by the US Department of Education.

COERLL creates educational materials designed for dissemination over the Internet. Called open educational resources (OERs), the online language tools (courses, reference grammars, assessment tools, etc.) are of great interest to me.

The material is free for anyone to use but may require permission to re-mix, improve, and redistribute. COERLL aims to promote a culture of collaboration. In addition, COERLL stated aims are to reframe foreign language education in terms of bilingualism and/or multilingualism.

I wish the university in London would host something similar. If offered in conjunction with a course such as the one that I took, possibly more could be accomplished. And, at the end of the course there could be an exam. Pass the exam and earn a credit from the university.

If you'd like to see what I am talking about, click the Le Vin de Vouvray link. This will take you to one of the COERLL French exercises posted by the University of Texas. I took the liberty of creating a vocabulary quiz in Quizlet using the vocabulary supplied with the Le Vin de Vouvray post.

I'm going to share a link to this post with one of the teachers at the French public school my granddaughter  attends. I'm seeking feedback on this open educational resource concept. I'm trying to decide whether I should proceed further in my attempt at interesting educators in London to offer something similar.

Are anticoagulants underused in Ontario?

In writing the following post, I came upon the paper How Can We Avoid a Stroke Crisis in Europe? If you do nothing more, read this paper. You found my blog because you were searching for information on anticoagulants, heart rhythm problems and risk of stroke. Read the linked paper. You may find it answers many of your questions.

When done, if you want to know more, read the rest of my post. There are also more links of interest.

Cheers,
Rockinon -- a patient with ongoing heart problems
___________________________________________________________________________

Are anticoagulants underused in Ontario? This is the question I asked myself upon learning that a friend in constant heart flutter was not taking an anticoagulant to lessen his chances of suffering a debilitating stroke.

I found an article in The American Journal of Medicine looking at this very question. I learned there are clear guidelines for managing atrial fibrillation and atrial flutter with recommendations for anticoagulation based on a patient's overall stroke risk. I also learned that the guidelines are not always being followed.

In a study of more than 170,000 patients in the States, less than 50% of high-risk patients were given anticoagulant therapy. The study concluded that the anticoagulation guidelines are not being routinely followed in clinical practice. The study did not conclude this was resulting in harm to untreated patients but decided another study, one looking at treatment outcomes, was warranted.

I can understand doctors being hesitant to immediately give anticoagulants to all patients with high CHADS₂ scores. Although I am now taking an anticoagulant daily, it was a tough call for my doctors.

I have microbleeding in the brain, discovered during an MRI scan. For a very good discussion of the significance of cerebral microbleeds read the article Cerebral microbleeds: a new dilemma in stroke medicine posted in the Journal of the Royal Society of Medicine. In my case, as in all cases, doctors must weight the risks vs. the benefits of various treatments. All too often the answer is a trade-off.

Clearly, a slightly elevated CHADS₂ score is not always enough to convince doctors anticoagulants are the best response. They see the risk/benefit ratio as not favouring the immediate use of a blood thinner (an inaccurate name for anticoagulants.) I don't envy doctors. They find themselves forced to choose between a rock and a hard place every day.

So, should more Ontario patients be on anticoagulants to protect them against stroke? It is hard to say for certain but the answer may well be yes. The Canadian doctors, like their American counterparts, may be too conservative, too timid. In steering their patients down a path that avoids the complications resulting from the use of blood thinners, their patients may be on the road to a stroke.

If you have a heart arrhythmia and are not on a blood thinner, you should ask your doctor why not. There may be good reasons for not giving you anticoagulant therapy but you should know what they are. To get a handle on your risk of a stroke, here is a link to a CHA₂DS₂-VASc Score calculator.

To better understand your risk of bleeding, here is a link to a HAS-BLED calculator. Taken together these two calculators point to the difficult decisions forced upon your doctor.

Lastly, not all abnormal heart rhythms are created equal. All arrhythmias do not result in equal risk of stroke. And atrial flutter, when occurring alone, does not carry the same increased risk of stroke as atrial fibrillation. That said, atrial flutter is often accompanied by periods of atrial fibrillation.

So, should my friend be taking an anticoagulant to lessen his risk of stroke? Maybe. He was on a blood thinner but stopped taking his medication on his own. Possibly his doctor senses his patient's fears and this tips the scales against recommending anticoagulants in the doctor's mind.

But atrial flutter is not benign. It is associated with an increase in overall mortality. According to a  posting on Patient.co.uk, persistent atrial flutter when left untreated can become chronic atrial fibrillation (AF). Even after treatment, I had my atrial flutter eradicated by undergoing an ablation procedure, I continue to take the powerful arrhythmia fighting drug sotalol to help insure my flutter does not return. I also continue to take Pradaxa, a blood thinner, twice a day.

Lastly, I wonder if the perceived dramatic increase in cost of anticoagulant therapy in recent years has influenced doctors, especially in the States. The old drug of choice, coumadin, is relatively inexpensive and safe. Unfortunately, it is also a fair amount of trouble. Regular blood work is necessary to insure the dosage is effective. The bothersome constant need for monitoring is one reason many patients quietly stop taking coumadin without consulting their doctors.

Newer drugs, like Pradaxa (dabigatran), cost more but do not require the expensive regular blood work. Some studies, such as one in Denmark, have found treatment with dabigatran only costs about 10% more than coumadin, with the increased cost of the medication the main driver of the added Pradaxa expense. I take Pradaxa to protect me against stroke while minimizing my chances of suffering a cranial bleed.

Minimizing the occurrence of strokes is a win-win situation. Both patients and society benefit from anticoagulant therapy in high-risk AF populations. A French study found the mean cost of a severe stroke was €34,809, and the risk of a severe stroke is what accompanies AF. The mean cost of a mild stroke in the study was €10,530. Clearly, dabigatran saves society money by preventing severe strokes in AF patients.

So, why do doctors shy away from prescribing blood thinners when the cost is not exorbitant and the benefits appear to be clear? One study pointed to a misplaced fear of bleeding, especially cranial bleeding. The fear of bleeding seems to trump the fear of stroke among medical professionals.

And so, in seeking treatment for heart rhythm problems there is one risk that is often overlooked: The risk that one's doctor has a personal aversion, an unsubstantiated fear, of the side-effects of the what should be one of the drugs of choice -- an anticoagulant.

NASA claims no ties to research paper

National Post: Tuesday, March 18, 2014

It was quite the story: A NASA-funded study predicted the end of the civilized world as we know it. The controversial report calculated that our global civilization is headed for annihilation. The sky may not be falling now but come back in a few decades and bring a hard hat.

The Independent: Sun., Mar. 3, 2014

The story, published by The Independent and The Guardian in Britain, was picked up by The Huffington Post and immediately went viral. The story was repeated by media outlets around the world. Even NASA entered the fray with a comment. This was not unexpected as scores of media outlets around the globe reported on the NASA-funded and oh-so-damning report.

Did the NASA statement contain any surprises? In a word, yes. For one thing, NASA called the media reports "erroneous." The soon-to-be released study "was not solicited, directed or reviewed by NASA. It is an independent study . . . ," NASA claimed.

NASA was in damage-control mode, distancing itself from the story. A Google search found a link to the scholarly paper. The authors write, "This work was partially funded through NASA/GSFC grant NNX12AD03A."

The National Socio-Environmental Synthesis Center (SESYNC), one of the sponsors of the paper, reports:

" [Safa] Motesharrei [one of the authors of the paper] received minor support from NASA to develop a coupled earth system model. Some of this funding was spent on the mathematical development of the HANDY model."

The paper is not only connected to NASA by some minor funding, one of the report's authors, Eugenia Kalnay, was branch head at NASA Goddard Space Flight Center prior to heading off to the University of Maryland.

The media reports may have overstated the NASA connection but the NASA press release underplays the connection the space agency has to this University of Maryland paper. The respected-research-patina conveyed by an association with NASA is certainly there. The reason for NASA's backpedaling is clear.

The study in question found that the ongoing economic stratification of society -- think of the one percenters and the rich-get-richer world endorsed by right wing capitalist Kevin O'Leary on CBC -- makes the collapse of civilization almost unavoidable. Major policy changes to reduce inequality are desperately needed, according to the authors.

I find one of the most interesting features about this story is not how far and fast it spread but the limits to growth it encountered. Even the Club of Rome might find this interesting. I could find no evidence that Sun Media, Canada's right wing newspaper chain, featured the story at all.

Does U.S. educated reporter hate Canadian health care system?

The headline screams "Crohn's research at Robarts hits world stage." Is the headline true? Yes. Is it the whole story? Not by a long shot.

Dr. Brian Feagan is the director of Robarts Clinical Trials at the Robarts Research Institute in London, Ontario. Last year Feagan was among those awarded the 2013 Scientific Achievement Award by the Crohn’s & Colitis Foundation of America (CCFA). Feagan has long been known for, as they say, pushing the needle forward in the quest for cures to these diseases.

The man is amazing. A quick Google search shows he has been at the forefront of inflammatory bowel disease research since late in the last century at least. His latest work is, not surprisingly, a continuation and a validation of research which has attracted global interest for years. He is a longtime player on the world health care stage.

Londoners should be proud of medical scientists like Feagan and proud of the work being done at the Robarts Research Institute. Researchers like Feagan and their studies are among the reasons I have the institute on my short list for an annual charitable donation. Because of the work done there, I am increasing my donation this year.

If you have been reading the series of articles run by The London Free Press and carried by Sun Media across the chain, you would think that Canadians are receiving second rate health care when compared to what is available south of the border in the States. The story tells readers "many provinces won't pay" for an aggressive approach for treating Crohn's disease.

A quick Google search turned up this online post by a woman in Salt Lake City, Utah:

In November, my new gastroenterologist . . . started me on Humira. It's a biological medication to decrease inflammation that has been successful to treat some people's Crohn's disease. . . .

The insurance denied the claim when the the pharmacy tried to get payment, because after a couple of refills at a local pharmacy, it's only covered when it comes from a "specialty pharmacy," called Acredo. After three hours either talking with people at Acredo, the specialty pharmacy, or having my doctor's office or the University pharmacy techs talk with people at Acredo and the insurance company, I left without the medication.

The patient ended her tirade saying, "Sigh. I wish private enterprise wouldn't get between patients and treatment"

Yes, some provinces resist paying for aggressive and expensive treatments for Crohn's disease as the first line approach -- but so do many private insurance plans around the globe. These are often plans that the patients thought were excellent until they were denied coverage for a drug like Humira.

I will leave the last word to Beth, the lady with Crohn's disease that I quoted out of Salt Lake City.

"I shouldn't be surprised [at the denial of coverage], since Anthem Blue Cross is beholden to stockholders before patients. Private business, in my opinion, is NOT always the best way to get things done, especially when it comes to health issues."

The Free Press article wasn't wrong. It wasn't error filled. But it wasn't balanced either.